Reactome | Chen, ZJ

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Chen, ZJ Show undefined attributes

created	[InstanceEdit:2395997] Shamovsky, V, 2012-07-09
dbId	2395999
displayName	Chen, ZJ
firstname	Zhijian J
initial	ZJ
publications	[LiteratureReference:8869457] Ubiquitination in signaling to and activation of IKK [LiteratureReference:2396006] STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway [LiteratureReference:9860251] IKK? is an IRF5 kinase that instigates inflammation [LiteratureReference:9645463] TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6 [LiteratureReference:9658379] BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver [LiteratureReference:3244594] Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway [LiteratureReference:6793311] Direct, noncatalytic mechanism of IKK inhibition by A20 [LiteratureReference:9705328] IKK?-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex [LiteratureReference:2408399] Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING [LiteratureReference:3244591] Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA [LiteratureReference:8982064] Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses [LiteratureReference:9715422] MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades [LiteratureReference:9749512] NLRX1 negatively regulates TLR-induced NF-?B signaling by targeting TRAF6 and IKK [LiteratureReference:9731462] Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation [LiteratureReference:9932516] Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm
schemaClass	Person
surname	Chen

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