Reactome | metalloendopeptidase activity of Adam10 [plasma membrane]

Schema > CatalystActivity > Entries

activity	[GO_MolecularFunction:1791] metalloendopeptidase activity
catalyzedEvent	[Reaction:R-MMU-2193065] Adam10 cleaves Notch2 - Mus musculus [BlackBoxEvent:R-MMU-9604278] Adam10 cleaves Notch4 - Mus musculus [Reaction:R-NUL-209162] Murine ADAM10 cleaves Notch at the S2 site producing transmembrane spanning NEXT and ligand-bound NECD - Mus musculus
created	[InstanceEdit:205681] Williams, MG, 2006-09-21 15:05:28
dbId	208925
displayName	metalloendopeptidase activity of Adam10 [plasma membrane]
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
physicalEntity	[EntityWithAccessionedSequence:R-MMU-179824] Adam10 [plasma membrane]
schemaClass	CatalystActivity

(catalystActivity)

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