Reactome | Witthuhn, BA

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Witthuhn, BA Show undefined attributes

created	[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
dbId	207948
displayName	Witthuhn, BA
initial	BA
publications	[LiteratureReference:208315] JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin [LiteratureReference:1302709] Signaling by the cytokine receptor superfamily: JAKs and STATs [LiteratureReference:893525] Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction [LiteratureReference:1112505] Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130 [LiteratureReference:873856] Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop [LiteratureReference:879929] Signaling through the hematopoietic cytokine receptors [LiteratureReference:873904] Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor [LiteratureReference:873845] Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state [LiteratureReference:873895] Determination of the transphosphorylation sites of Jak2 kinase [LiteratureReference:879936] JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region [LiteratureReference:982795] Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase [LiteratureReference:1295489] Defective lymphoid development in mice lacking Jak3 [LiteratureReference:1067644] Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components [LiteratureReference:909644] The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction [LiteratureReference:451897] Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID [LiteratureReference:451901] Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
schemaClass	Person
surname	Witthuhn

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