Activated PLCG translocates to the plasmamembrane and intera...

created [InstanceEdit:2028831] Garapati, P V, 2012-01-04
dbId 2028787
displayName Activated PLCG translocates to the plasmamembrane and intera...
schemaClass Summation
text Activated PLCG translocates to the plasmamembrane and interacts with the inositol ring of the membrane bound phosphatidylinositol 4,5-bisphosphate (PIP2) with its PH domain. The active enzyme promotes intracelllular signaling by catalysing the hydrolysis of PIP2 to generate the second messengers IP3 and DAG.
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