Reactome | Insertion of a connexon into the cell membrane results in th...

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created	[InstanceEdit:190826] Matthews, L, 2007-01-09 12:52:19
dbId	190878
displayName	Insertion of a connexon into the cell membrane results in th...
literatureReference	[LiteratureReference:190468] A freeze-fracture paradigm of the mechanism for delivery and insertion of gap junction particles into the plasma membrane [LiteratureReference:190836] Lateral diffusion of membrane-spanning and glycosylphosphatidylinositol-linked proteins: toward establishing rules governing the lateral mobility of membrane proteins [LiteratureReference:190727] Regulation of connexin biosynthesis, assembly, gap junction formation, and removal
modified	[InstanceEdit:194781] Matthews, L, 2007-03-27 16:29:06
schemaClass	Summation
text	Insertion of a connexon into the cell membrane results in the formation of a hemi-channel. This channel permits direct exchanges between cell cytoplasm and extracellular matrix (Figure 3). Freeze-fracture electron microscopy studies have revealed that cytoplasmic vesicles can fuse with the plasma membrane to permit connexon insertion (Shivers and Bowman 1985).

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