5-aminolevulinate (dALA) is transported from the mitochondri...

created [InstanceEdit:189470] Jassal, B, 2006-11-20 11:41:56
dbId 189462
displayName 5-aminolevulinate (dALA) is transported from the mitochondri...
modified [InstanceEdit:9853619] D'Eustachio, Peter, 2023-11-17
schemaClass Summation
text 5-aminolevulinate (dALA) is transported from the mitochondrial matrix to the cytosol. While indirect studies suggest that activity of the ABCB10 transporter is correlated with dALA production (Bayeva et al. 2013), biochemical studies of the purified protein indicate that dALA is not a transported substrate (Qiu et al. 2015), leaving the transporter that mediates dALA export to the cytosol and the role of ABCB10 in heme biosynthesis unknown.
Cite Us!