Reactome | Yusoff, P

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Yusoff, P Show undefined attributes

created	[InstanceEdit:183010] Jassal, B, 2006-07-21 10:19:47
dbId	183038
displayName	Yusoff, P
firstname	Permeen
initial	P
modified	[InstanceEdit:1268148] Rothfels, K, 2011-05-09
publications	[LiteratureReference:1295617] Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf [LiteratureReference:1295597] The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes [LiteratureReference:934564] Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation [LiteratureReference:934622] A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation [LiteratureReference:8876990] Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin [LiteratureReference:1295611] Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain [LiteratureReference:188628] Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling [LiteratureReference:1268103] Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function
schemaClass	Person
surname	Yusoff

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