Reactome | Wong, ES

Schema > Person > Entries

created	[InstanceEdit:183010] Jassal, B, 2006-07-21 10:19:47
dbId	182996
displayName	Wong, ES
firstname	Esther Sook Miin
initial	ES
modified	[InstanceEdit:1268146] Rothfels, K, 2011-05-09
publications	[LiteratureReference:934613] Evidence for direct interaction between Sprouty and Cbl [LiteratureReference:188628] Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling [LiteratureReference:1295611] Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain [LiteratureReference:1268103] Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function [LiteratureReference:1295597] The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes [LiteratureReference:183032] Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation [LiteratureReference:1295617] Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf
schemaClass	Person
surname	Wong

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