Reactome | At the beginning of this reaction, 1 molecule of 'RNA primer...

Schema > Summation > Entries

created	[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
dbId	178666
displayName	At the beginning of this reaction, 1 molecule of 'RNA primer...
literatureReference	[LiteratureReference:8984666] A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome [LiteratureReference:8984656] Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing [LiteratureReference:8984605] Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication [LiteratureReference:169462] Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p
modified	[InstanceEdit:8984615] Duenas, Corina, 2017-04-10
schemaClass	Summation
text	At the beginning of this reaction, 1 molecule of 'RNA primer-DNA primer:origin duplex' is present. At the end of this reaction, 1 molecule of 'DNA polymerase alpha:primase', and 1 molecule of 'RNA primer-DNA primer:origin duplex with DNA damage' are present. This reaction takes place in the 'nucleus' (Gambus et al. 2009, Remus et al. 2009, Chattopadhyay et al.2007, Fien et al. 2004).

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