Like all viruses, HIV-1 must co-opt the host cell macromolec...

created [InstanceEdit:170617] Gopinathrao, G, 2006-01-08 02:23:40
dbId 170607
displayName Like all viruses, HIV-1 must co-opt the host cell macromolec...
modified [InstanceEdit:182886] D'Eustachio, P, 2006-07-20 16:22:44
schemaClass Summation
text Like all viruses, HIV-1 must co-opt the host cell macromolecular transport and processing machinery. HIV-1 Vpr and Rev proteins play key roles in this co-optation. Efficient HIV-1 replication likewise requires evasion of APOBEC3G-mediated mutagenesis of reverse transcripts, a process mediated by the viral Vif protein.
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