Reactome | Fabbro, D

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created	[InstanceEdit:1678882] Rothfels, K, 2011-10-19
dbId	1678881
displayName	Fabbro, D
firstname	Doriano
initial	D
publications	[LiteratureReference:9028747] THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors [LiteratureReference:9699355] Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia [LiteratureReference:9669059] Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412 [LiteratureReference:9652318] AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity [LiteratureReference:9676836] Effects of PKC412, nilotinib, and imatinib against GIST-associated PDGFRA mutants with differential imatinib sensitivity [LiteratureReference:9671383] PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects [LiteratureReference:2399826] Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity [LiteratureReference:2077411] FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies [LiteratureReference:1679952] PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder [LiteratureReference:2399821] Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor
schemaClass	Person
surname	Fabbro

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