Reactome | Latz, E

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Latz, E Show undefined attributes

created	[InstanceEdit:165911] de Bono, B, 2005-08-11 15:33:55
dbId	165912
displayName	Latz, E
initial	E
publications	[LiteratureReference:1679137] TLR9 signals after translocating from the ER to CpG DNA in the lysosome [LiteratureReference:2445249] Ligand-induced conformational changes allosterically activate Toll-like receptor 9 [LiteratureReference:874092] Intracellular DNA recognition [LiteratureReference:181956] Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling [LiteratureReference:975484] The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling [LiteratureReference:1964479] RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate [LiteratureReference:166859] IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway [LiteratureReference:165909] LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters [LiteratureReference:874003] AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC [LiteratureReference:2206238] Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity [LiteratureReference:873948] Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization [LiteratureReference:874004] The NALP3 inflammasome is involved in the innate immune response to amyloid-beta [LiteratureReference:936987] An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4 [LiteratureReference:1834943] IFI16 is an innate immune sensor for intracellular DNA [LiteratureReference:873992] The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses [LiteratureReference:844628] Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
schemaClass	Person
surname	Latz

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