Reactome | Tempst, P

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created	[InstanceEdit:162394] de Bono, B, 2005-03-24 12:05:55
dbId	162385
displayName	Tempst, P
firstname	Paul
initial	P
modified	[InstanceEdit:200032] D'Eustachio, P, 2007-07-13 20:48:01
publications	[LiteratureReference:1022081] Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3 [LiteratureReference:3301279] Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo [LiteratureReference:3215351] Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes [LiteratureReference:1222629] Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein [LiteratureReference:870535] Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway [LiteratureReference:212244] Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein [LiteratureReference:391797] Function in protein folding of TRiC, a cytosolic ring complex containing TCP-1 and structurally related subunits [LiteratureReference:200046] Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart [LiteratureReference:5211373] Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin [LiteratureReference:5084092] Role of hPHF1 in H3K27 methylation and Hox gene silencing [LiteratureReference:1008209] The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene [LiteratureReference:4687073] JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor [LiteratureReference:4687085] The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase [LiteratureReference:5634728] Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain [LiteratureReference:1222559] Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates [LiteratureReference:5696603] Regulation of cell cycle progression and gene expression by H2A deubiquitination [LiteratureReference:4687034] The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36 [LiteratureReference:3214867] Histone demethylation by a family of JmjC domain-containing proteins [LiteratureReference:4687056] The retinoblastoma binding protein RBP2 is an H3K4 demethylase [LiteratureReference:6807641] A v-SNARE implicated in intra-Golgi transport [LiteratureReference:212296] Role of histone H3 lysine 27 methylation in Polycomb-group silencing [LiteratureReference:6783300] A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation [LiteratureReference:381274] Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha [LiteratureReference:3301890] mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression [LiteratureReference:5669204] Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo [LiteratureReference:212444] A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system [LiteratureReference:5697043] Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage [LiteratureReference:8931511] The human PAF complex coordinates transcription with events downstream of RNA synthesis [LiteratureReference:199376] Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton [LiteratureReference:913454] A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells [LiteratureReference:5334178] DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA [LiteratureReference:215119] Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex [LiteratureReference:6805732] Regulation of p53 activity through lysine methylation [LiteratureReference:163353] Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death [LiteratureReference:3247557] Histone deimination antagonizes arginine methylation [LiteratureReference:2301212] PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin [LiteratureReference:6807121] NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN [LiteratureReference:2176494] Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling [LiteratureReference:5683931] WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity [LiteratureReference:5696953] USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing [LiteratureReference:162390] Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B [LiteratureReference:1675877] The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101 [LiteratureReference:3301340] Purification and characterization of the human elongator complex [LiteratureReference:5687167] Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs [LiteratureReference:5690089] Ubiquitination regulates PTEN nuclear import and tumor suppression [LiteratureReference:8934723] Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity [LiteratureReference:6793071] MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome [LiteratureReference:196684] Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices
schemaClass	Person
surname	Tempst

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