Reactome | Molloy, S S

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created	[InstanceEdit:159817] D'Eustachio, P, 2005-03-17 16:24:57
dbId	159839
displayName	Molloy, S S
firstname	Sean S
initial	S S
modified	[InstanceEdit:5205694] D'Eustachio, Peter, 2013-12-05
publications	[LiteratureReference:5205696] Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen [LiteratureReference:5205729] Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin [LiteratureReference:159838] Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage [LiteratureReference:159802] Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail
schemaClass	Person
surname	Molloy

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