Reactome | Alnemri, ES

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Alnemri, ES Show undefined attributes

dbId	141891
displayName	Alnemri, ES
firstname	Emad S
initial	ES
publications	[LiteratureReference:844628] Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression [LiteratureReference:211630] Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity [LiteratureReference:141214] Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. [LiteratureReference:874032] AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA [LiteratureReference:9686078] Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death [LiteratureReference:9689630] Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation [LiteratureReference:877365] The PYRIN-CARD protein ASC is an activating adaptor for caspase-1 [LiteratureReference:873970] Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1 [LiteratureReference:9839099] Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi [LiteratureReference:9710645] Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 [LiteratureReference:9627068] Mechanism of XIAP-mediated inhibition of caspase-9 [LiteratureReference:6805408] CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis [LiteratureReference:879199] Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants [LiteratureReference:141216] Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
schemaClass	Person
surname	Alnemri

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