Reactome | Thompson, CB

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Thompson, CB Show undefined attributes

created	[InstanceEdit:140377] Gopinathrao, G, 2004-08-18 11:49:08
dbId	140401
displayName	Thompson, CB
firstname	Craig B
initial	CB
modified	[InstanceEdit:879981] D'Eustachio, P, 2010-06-25
publications	[LiteratureReference:389243] T-cell regulation by CD28 and CTLA-4 [LiteratureReference:169969] Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death [LiteratureReference:434955] Structural analysis of CTLA-4 function in vivo [LiteratureReference:140457] Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death [LiteratureReference:140395] tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c [LiteratureReference:9927337] CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms [LiteratureReference:6805462] AMP-activated protein kinase induces a p53-dependent metabolic checkpoint [LiteratureReference:9763328] Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase [LiteratureReference:879775] AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation [LiteratureReference:6789410] In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA [LiteratureReference:9653428] PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis [LiteratureReference:879979] Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
schemaClass	Person
surname	Thompson

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