| accession | 0003994 |
| databaseName | GO |
| dbId | 12740 |
| definition | Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate. |
| displayName | aconitate hydratase activity |
| ecNumber | 4.2.1.3 |
| modified | [InstanceEdit:9676538] Cook, Justin, 2020-02-17 |
| name | aconitate hydratase activity |
| referenceDatabase | [ReferenceDatabase:1] GO |
| schemaClass | GO_MolecularFunction |
| url | https://www.ebi.ac.uk/QuickGO/term/GO:0003994 |
© 2026 Reactome