Pol II pausing is believed to result from reversible backtra...

created [InstanceEdit:113847] Gopinathrao, G, 2004-06-23 11:10:00
dbId 113851
displayName Pol II pausing is believed to result from reversible backtra...
literatureReference
modified [InstanceEdit:167861] Matthews, L, 2005-11-09 17:01:53
schemaClass Summation
text Pol II pausing is believed to result from reversible backtracking of the Pol II enzyme complex by ~2 to 4 nucleotides. This leads to misaligned 3'-OH terminus that is unable to be an acceptor for the incoming NTPs in synthesis of next phosphodiester bond (reviewed by Shilatifard et al., 2003).
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