Reactome | Guan, KL

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Guan, KL Show undefined attributes

dbId	111055
displayName	Guan, KL
firstname	Kun-Liang
initial	KL
modified	[InstanceEdit:2028234] D'Eustachio, P, 2011-12-23
publications	[LiteratureReference:182600] Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4 [LiteratureReference:182595] Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function [LiteratureReference:5672273] Regulation of Raf through phosphorylation and N terminus-C terminus interaction [LiteratureReference:110054] Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. [LiteratureReference:208207] Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues [LiteratureReference:5672419] Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601 [LiteratureReference:400683] The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding [LiteratureReference:416545] Semaphorins command cells to move [LiteratureReference:392036] Mechanisms of regulating the Raf kinase family [LiteratureReference:5672243] Positive and negative regulation of Raf kinase activity and function by phosphorylation [LiteratureReference:381848] TSC2 mediates cellular energy response to control cell growth and survival [LiteratureReference:5693185] Amino acid signalling upstream of mTOR [LiteratureReference:9928277] Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation [LiteratureReference:9623443] Negative regulation of the forkhead transcription factor FKHR by Akt [LiteratureReference:2028641] The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version [LiteratureReference:400678] The semaphorin receptor plexin-B1 specifically interacts with active Rac in a ligand-dependent manner [LiteratureReference:8943702] PTEN acetylation modulates its interaction with PDZ domain [LiteratureReference:165681] Signaling by target of rapamycin proteins in cell growth control [LiteratureReference:532189] Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling [LiteratureReference:5665841] AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 [LiteratureReference:5665936] The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR [LiteratureReference:451353] DSCAM functions as a netrin receptor in commissural axon pathfinding [LiteratureReference:416556] The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG [LiteratureReference:199381] TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling [LiteratureReference:8954460] Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth [LiteratureReference:2028252] Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein [LiteratureReference:2032764] TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition [LiteratureReference:2028663] TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway [LiteratureReference:5679238] ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase [LiteratureReference:8951887] TEAD mediates YAP-dependent gene induction and growth control [LiteratureReference:373423] Activation of FAK and Src are receptor-proximal events required for netrin signaling [LiteratureReference:2028574] Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
schemaClass	Person
surname	Guan

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