Reactome | aldehyde-lyase activity of SHMT1 tetramer [cytosol]

Schema > CatalystActivity > Entries

activeUnit	[DefinedSet:R-SCE-71242-3] Homologues of PXLP-SHMT1 [cytosol] - Saccharomyces cerevisiae
activity	[GO_MolecularFunction:2020] aldehyde-lyase activity
catalyzedEvent	[Reaction:R-SCE-71249] SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly - Saccharomyces cerevisiae [Reaction:R-SCE-200735] SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG - Saccharomyces cerevisiae [Reaction:R-SCE-200651] 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine - Saccharomyces cerevisiae
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11081527
displayName	aldehyde-lyase activity of SHMT1 tetramer [cytosol]
physicalEntity	[Complex:R-SCE-71243] SHMT1 tetramer [cytosol]
schemaClass	CatalystActivity

(catalystActivity)