Reactome | arachidonate 12(S)-lipoxygenase activity of ALOX12:Fe2+ [cytosol]

Schema > CatalystActivity > Entries

activity	[GO_MolecularFunction:7165] arachidonate 12(S)-lipoxygenase activity
catalyzedEvent	[Reaction:R-SSC-9024983] ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA - Sus scrofa [Reaction:R-SSC-9026007] ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 - Sus scrofa [Reaction:R-SSC-9026006] ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 - Sus scrofa [Reaction:R-SSC-9025957] ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 - Sus scrofa [Reaction:R-SSC-2161948] Arachidonate is converted to 12-oxoETE by ALOX12 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10501826
displayName	arachidonate 12(S)-lipoxygenase activity of ALOX12:Fe2+ [cytosol]
physicalEntity	[Complex:R-SSC-2142793] ALOX12:Fe2+ [cytosol]
schemaClass	CatalystActivity

(catalystActivity)