Reactome | (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity of HSD17B4 dimer [peroxisomal matrix]

Schema > CatalystActivity > Entries

activity	[GO_MolecularFunction:11645] (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
catalyzedEvent	[Reaction:R-RNO-193455] (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA - Rattus norvegicus [Reaction:R-RNO-193508] (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA - Rattus norvegicus [Reaction:R-RNO-389995] 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ - Rattus norvegicus [Reaction:R-RNO-390251] HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10122386
displayName	(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity of HSD17B4 dimer [peroxisomal matrix]
physicalEntity	[Complex:R-RNO-389999] HSD17B4 dimer [peroxisomal matrix]
schemaClass	CatalystActivity

(catalystActivity)