Circadian transcriptional pathway atlas highlights a proteasome switch in intermittent fasting

Reactome pathway gene sets in the MSigDB facilitated identification of the liver proteasome transcriptional switch that acts as the fasting timer in intermittent fasting in work published by Wei et al. in Cell Reports on October 25, 2022. The authors suggest that a 16-hour interval in intermittent fasting may be most beneficial for health.