Reactome | stub1 [cytosol]

stub1 [cytosol]

Stable Identifier

R-XTR-975970

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

STUB1, Q0V9Q4

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Intracellular signaling by second messengers (Xenopus tropicalis)
  - PIP3 activates AKT signaling (Xenopus tropicalis)
    - PTEN Regulation (Xenopus tropicalis)
      - Regulation of PTEN stability and activity (Xenopus tropicalis)
        
        NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Xenopus tropicalis)
        
        NEDD4,STUB1,WWP2 and XIAP [cytosol] (Xenopus tropicalis)
        
        stub1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q0V9Q4

Gene Names

stub1

Reference Genes

BioGPS Gene:779800 stub1

ENSEMBL:ENSXETG00000032697

KEGG:xtr:779800 stub1

Monarch:779800 stub1

NCBI Gene:779800 stub1

UCSC:Q0V9Q4 stub1

Reference Transcript

RefSeq:NM_001078879.1 stub1

Other Identifiers

779800

GO:0000209

GO:0003824

GO:0004842

GO:0005634

GO:0005737

GO:0005739

GO:0006281

GO:0006515

GO:0006974

GO:0007165

GO:0009893

GO:0016567

GO:0016740

GO:0030018

GO:0030163

GO:0043161

GO:0045862

GO:0051087

GO:0061630

GO:0071218

GO:0140096

Participates

as an output of

STUB1 polyubiquitinates RUNX2 (Xenopus tropicalis)

as an input of

RUNX2 binds STUB1 (Xenopus tropicalis)

as a component of

as a member of

NEDD4,STUB1,WWP2 and XIAP [cytosol] (Xenopus tropicalis)

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Xenopus tropicalis)

Inferred From

STUB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001072347.1

ENSEMBL

ENSXETP00000062266, ENSXETG00000032697, ENSXETT00000061675

Xenbase

XB-GENE-966697