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nlrc5 [cytosol]
Stable Identifier
R-XTR-9750938
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
K63polyUb-NLRC5, A0A803J229
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-1 family signaling (Xenopus tropicalis)
Interleukin-1 signaling (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Innate Immune System (Xenopus tropicalis)
Toll-like Receptor Cascades (Xenopus tropicalis)
Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
MyD88-independent TLR4 cascade (Xenopus tropicalis)
TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
TAK1-dependent IKK and NF-kappa-B activation (Xenopus tropicalis)
Regulation of NF-kappa B signaling (Xenopus tropicalis)
NLRC5 binds IKBKB and CHUK (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
nlrc5 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A803J229
Gene Names
nlrc5
Reference Genes
BioGPS Gene:101730579 nlrc5
ENSEMBL:ENSXETG00000039569
Monarch:101730579 nlrc5
NCBI Gene:101730579 nlrc5
UCSC:A0A803J229 nlrc5
Reference Transcript
RefSeq:XM_031900763.1 nlrc5
RefSeq:XM_031900762.1 nlrc5
RefSeq:XM_031900764.1 nlrc5
Other Identifiers
101730579
GO:0000166
GO:0005524
Participates
as an output of
TRAF2,6 ubiquitinates NLRC5 (Xenopus tropicalis)
as an input of
USP14 deubiquitinates NLRC5 (Xenopus tropicalis)
This entity regulates
Negatively
NLRC5 binds IKBKB and CHUK
(Xenopus tropicalis)
Other forms of this molecule
nlrc5 [cytosol]
Inferred From
K63polyUb-NLRC5 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 1178 (in Homo sapiens)
Coordinate
1178
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
XP_031756622.1
,
XP_031756623.1
,
XP_031756624.1
ENSEMBL
ENSXETT00000107635
,
ENSXETP00000101870
,
ENSXETG00000039569
Xenbase
XB-GENE-6462433
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