Reactome | areg [clathrin-coated endocytic vesicle membrane]

areg [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-XTR-9628809

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

AREG(101-187), F6VBJ9

Locations in the PathwayBrowser

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Vesicle-mediated transport (Xenopus tropicalis)

- Membrane Trafficking (Xenopus tropicalis)
  - Clathrin-mediated endocytosis (Xenopus tropicalis)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        areg [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        areg [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        areg [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2:REPS2 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands:Ub-p-6Y-EGFR:p-Y371-CBL:GRB2 [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)
        
        areg [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6VBJ9

Gene Names

areg

Reference Genes

BioGPS Gene:100145251 areg

ENSEMBL:ENSXETG00000033272

KEGG:xtr:100145251 areg

Monarch:100145251 areg

NCBI Gene:100145251 areg

UCSC:F6VBJ9 areg

Reference Transcript

RefSeq:NM_001126733.1 areg

Other Identifiers

100145251

GO:0005154

GO:0005615

GO:0007165

GO:0007173

GO:0008083

GO:0008284

GO:0016020

GO:0048018

GO:0098772

Participates

as a member of

EGF-like ligands [clathrin-coated endocytic vesicle membrane] (Xenopus tropicalis)

Other forms of this molecule

areg [ER to Golgi transport vesicle membrane]

areg [endoplasmic reticulum membrane]

areg [extracellular region]

Inferred From

AREG(101-187) [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001120205.1

ENSEMBL

ENSXETG00000033272, ENSXETT00000053491, ENSXETP00000053491

Xenbase

XB-GENE-22061202