Reactome | znf143 [nucleoplasm]

znf143 [nucleoplasm]

Stable Identifier

R-XTR-83837

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

ZNF143, Q58DZ6

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - RNA polymerase II transcribes snRNA genes (Xenopus tropicalis)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - Integrator complex processes the 3' end of snRNA (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Xenopus tropicalis)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Xenopus tropicalis)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
    - SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Xenopus tropicalis)
      - POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
- RNA Polymerase III Transcription (Xenopus tropicalis)
  - RNA Polymerase III Transcription Initiation (Xenopus tropicalis)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Xenopus tropicalis)
      - Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter (Xenopus tropicalis)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Xenopus tropicalis)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Xenopus tropicalis)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Xenopus tropicalis)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Xenopus tropicalis)
        
        znf143 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q58DZ6

Gene Names

znf143

Reference Genes

BioGPS Gene:595042 znf143

ENSEMBL:ENSXETG00000024199

KEGG Gene (Xenopus tropicalis):595042 znf143

Monarch:595042 znf143

NCBI Gene:595042 znf143

Reference Transcript

RefSeq:NM_001030483.1 znf143

Participant Of

input

Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter

hasComponent

Inferred From

ZNF143 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001025654.1

Cite Us!