Reactome | rps4x [cytosol]

rps4x [cytosol]

Stable Identifier

R-XTR-72375

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

RPS4X, A0A8J1IN17

Locations in the PathwayBrowser

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Metabolism of RNA (Xenopus tropicalis)

- Nonsense-Mediated Decay (NMD) (Xenopus tropicalis)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Xenopus tropicalis)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Xenopus tropicalis)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
    - SMG6 hydrolyzes mRNA with premature termination codon (Xenopus tropicalis)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Xenopus tropicalis)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Xenopus tropicalis)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Xenopus tropicalis)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Xenopus tropicalis)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Xenopus tropicalis)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Xenopus tropicalis)
        
        80S ribosome [cytosol] (Xenopus tropicalis)
        
        40S ribosomal complex [cytosol] (Xenopus tropicalis)
        
        rps4x [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A8J1IN17

Gene Names

rps4x

Reference Genes

BioGPS Gene:394507 rps4x

ENSEMBL:ENSXETG00000027073

KEGG:xtr:394507 rps4x

Monarch:394507 rps4x

NCBI Gene:394507 rps4x

UCSC:A0A8J1IN17 rps4x

Other Identifiers

394507

GO:0003723

GO:0003735

GO:0005198

GO:0005737

GO:0005840

GO:0006412

GO:0019843

GO:0022627

GO:1990904

Participates

as a component of

Other forms of this molecule

rps4x [nucleoplasm]

rps4x [cytosol]

Inferred From

RPS4X,RPS4Y1,RPS4Y2 [cytosol] (Homo sapiens)

RPS4X [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_031746140.1, NP_988912.1

ENSEMBL

ENSXETP00000056755, ENSXETP00000066377, ENSXETG00000027073, ENSXETT00000105051, ENSXETT00000056755

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