Reactome | iqcb1 [cytosol]

iqcb1 [cytosol]

Stable Identifier

R-XTR-5626648

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

IQCB1, F7CAK5

Locations in the PathwayBrowser

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Organelle biogenesis and maintenance (Xenopus tropicalis)

- Cilium Assembly (Xenopus tropicalis)
  - Assembly of the 9+0 primary cilium (Xenopus tropicalis)
    - Anchoring of the basal body to the plasma membrane (Xenopus tropicalis)
      - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
      - C2CD3 binds the mother centriole (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
      - CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Xenopus tropicalis)
        
        basal body:transition zone proteins [cytosol] (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Xenopus tropicalis)
        
        basal body:transition zone proteins [cytosol] (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
      - CP110 and CEP97 dissociate from the centriole (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
      - MARK4 binds ODF2 in the centriole (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
        
        centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
      - RAB3IP stimulates nucleotide exchange on RAB8A (Xenopus tropicalis)
        
        basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Xenopus tropicalis)
        
        basal body:transition zone proteins [cytosol] (Xenopus tropicalis)
        
        basal body [cytosol] (Xenopus tropicalis)
        
        centrosome without CEP164, CCP110 or CEP97 [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
      - The distal appendage proteins recruit TTBK2 (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Xenopus tropicalis)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Xenopus tropicalis)
        
        mother centriole:C2CD3 [cytosol] (Xenopus tropicalis)
        
        mother centriole [cytosol] (Xenopus tropicalis)
        
        iqcb1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F7CAK5

Gene Names

iqcb1

Reference Genes

BioGPS Gene:780113 iqcb1

ENSEMBL:ENSXETG00000013923

Monarch:780113 iqcb1

NCBI Gene:780113 iqcb1

UCSC:F7CAK5 iqcb1

Reference Transcript

RefSeq:XM_031892743.1 iqcb1

Other Identifiers

780113

GO:0005516

GO:0005929

GO:0043226

GO:0044782

GO:0060271

Participates

as a component of

Inferred From

IQCB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_031748603.1

ENSEMBL

ENSXETT00000120353, ENSXETP00000115245, ENSXETG00000013923, ENSXETT00000030447, ENSXETP00000030447, ENSXETP00000111303, ENSXETT00000122503

Xenbase

XB-GENE-975373