Reactome | creb1 [nucleoplasm]

creb1 [nucleoplasm]

Stable Identifier

R-XTR-52777

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

CREB1, Q6NVP9

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - Signaling by Interleukins (Xenopus tropicalis)
    - Interleukin-17 signaling (Xenopus tropicalis)
      - MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
- Innate Immune System (Xenopus tropicalis)
  - Toll-like Receptor Cascades (Xenopus tropicalis)
    - Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
      - Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
      - Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
      - MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
      - MyD88-independent TLR4 cascade (Xenopus tropicalis)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        CREB phosphorylation (Xenopus tropicalis)
        
        RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)

Neuronal System (Xenopus tropicalis)

- Transmission across Chemical Synapses (Xenopus tropicalis)
  - Neurotransmitter receptors and postsynaptic signal transmission (Xenopus tropicalis)
    - Activation of NMDA receptors and postsynaptic events (Xenopus tropicalis)
      - Post NMDA receptor activation events (Xenopus tropicalis)
        
        CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Xenopus tropicalis)
        
        Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Xenopus tropicalis)
        
        creb1 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6NVP9

Gene Names

creb1

Reference Genes

BioGPS Gene:407934 creb1

ENSEMBL:ENSXETG00000016392

KEGG:xtr:407934 creb1

Monarch:407934 creb1

NCBI Gene:407934 creb1

UCSC:Q6NVP9 creb1

Reference Transcript

RefSeq:NM_213686.2 creb1

Other Identifiers

407934

GO:0000981

GO:0003677

GO:0003700

GO:0005634

GO:0006355

GO:0006357

GO:0035497

GO:0141156

GO:1990589

Participates

as an input of

Other forms of this molecule

phospho-creb1 [nucleoplasm]

Inferred From

CREB1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_998851.1

ENSEMBL

ENSXETG00000016392, ENSXETT00000119351, ENSXETP00000119437

Xenbase

XB-GENE-945015

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