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JAK1 [cytosol]
Stable Identifier
R-XTR-451898
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
F7DKS0
Locations in the PathwayBrowser
Expand all
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Interferon Signaling (Xenopus tropicalis)
Interferon alpha/beta signaling (Xenopus tropicalis)
Activation of JAK kinases (Xenopus tropicalis)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Recruitment of IFNAR1 (Xenopus tropicalis)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Xenopus tropicalis)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interferon gamma signaling (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
IFNGR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] (Xenopus tropicalis)
IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] (Xenopus tropicalis)
IFNGR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Signaling by CSF3 (G-CSF) (Xenopus tropicalis)
CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Xenopus tropicalis)
CSF3 dimer:CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
CSF3 dimer:CSFR:LYN:JAK1 binds CSFR:LYN:JAK1 (Xenopus tropicalis)
CSF3 dimer:2xCSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
CSF3 dimer:CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
CSF3 dimer:CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-10 signaling (Xenopus tropicalis)
IL10 dimer binds IL10RA:JAK1 (Xenopus tropicalis)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Xenopus tropicalis)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Xenopus tropicalis)
IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-12 family signaling (Xenopus tropicalis)
Interleukin-12 signaling (Xenopus tropicalis)
p-Y693-STAT4 dissociates after IL12:IL12R interaction (Xenopus tropicalis)
2xp-Y693-STAT4:IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Xenopus tropicalis)
IL12A:IL12B:IL12RB1:p-Y800-IL12RB2:p-Y-TYK2:p-JAK2 [plasma membrane] (Xenopus tropicalis)
p-Y800-IL12RB2:p-JAK2 [plasma membrane] (Xenopus tropicalis)
IL12RB1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-27 signaling (Xenopus tropicalis)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Xenopus tropicalis)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Xenopus tropicalis)
IL27RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-35 Signalling (Xenopus tropicalis)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
IL35:IL27RA:JAK1:IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
IL27RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Xenopus tropicalis)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-2 family signaling (Xenopus tropicalis)
Interleukin-2 signaling (Xenopus tropicalis)
IL2RB binds JAK1 (Xenopus tropicalis)
IL2RB:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-9 signaling (Xenopus tropicalis)
IL9R binds JAK1 (Xenopus tropicalis)
IL9R:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-20 family signaling (Xenopus tropicalis)
IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Xenopus tropicalis)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Xenopus tropicalis)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Xenopus tropicalis)
IFNL2,IFNL3:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL22 binds IL22RA1:JAK1 receptor complex (Xenopus tropicalis)
IL22:IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Xenopus tropicalis)
IL22:IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IL22:IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Xenopus tropicalis)
IL22:IL22RA1:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IL22:IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL22RA1 binds JAK1 (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Xenopus tropicalis)
IL26:IL20RA:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IL26:IL20RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IL20RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 binds IFNLR1 (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 binds IL20RA (Xenopus tropicalis)
IL20RA:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-6 family signaling (Xenopus tropicalis)
IL-6-type cytokine receptor ligand interactions (Xenopus tropicalis)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Xenopus tropicalis)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAKs bind LIFR (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAKs:LIFR [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAKs bind OSMR (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAKs:OSMR [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Interleukin-6 signaling (Xenopus tropicalis)
Assembly of hexameric IL-6 receptor (Xenopus tropicalis)
IL6 receptor hexamer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6 receptor trimer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL6 receptor trimer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
JAK activation (Xenopus tropicalis)
IL6 receptor hexamer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6 receptor trimer:JAKs [plasma membrane] (Xenopus tropicalis)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Xenopus tropicalis)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Xenopus tropicalis)
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
Other interleukin signaling (Xenopus tropicalis)
IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Xenopus tropicalis)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
JAK1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F7DKS0
Reference Genes
BioGPS Gene:100038172
ENSEMBL:ENSXETG00000020396
KEGG Gene (Xenopus tropicalis):100038172
Monarch:100038172
NCBI Gene:100038172
Reference Transcript
RefSeq:XM_002931596.5
RefSeq:XM_018093567.1
Other Identifiers
100038172
GO:0000166
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005524
GO:0005856
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0035556
GO:0036211
GO:0043226
GO:0140096
Participates
as a component of
IL12RB1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL27RA:JAK1 [plasma membrane] (Xenopus tropicalis)
CSF3R:LYN:JAK1 [plasma membrane] (Xenopus tropicalis)
IL22RA1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL10RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IL20RA:JAK1 [plasma membrane] (Xenopus tropicalis)
IFNLR1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL9R:JAK1 [plasma membrane] (Xenopus tropicalis)
IFNAR2:JAK1:STAT2 [plasma membrane] (Xenopus tropicalis)
IFNGR1:JAK1 [plasma membrane] (Xenopus tropicalis)
IL2RB:JAK1 [plasma membrane] (Xenopus tropicalis)
as an input of
IL22RA1 binds JAK1 (Xenopus tropicalis)
JAK1 binds IL20RA (Xenopus tropicalis)
JAK1 binds IFNLR1 (Xenopus tropicalis)
IL9R binds JAK1 (Xenopus tropicalis)
IL2RB binds JAK1 (Xenopus tropicalis)
as a member of
JAK1, JAK2, (TYK2) [cytosol] (Xenopus tropicalis)
Other forms of this molecule
phospho-p-Y1034,Y1035-JAK1 [cytosol]
phospho-p-JAK1 [cytosol]
phospho-p-Y1034-JAK1 [cytosol]
phospho-p-Y-JAK1 [cytosol]
Inferred From
JAK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_017949056.1
,
XP_002931642.1
Ensembl
ENSXETG00000020396
,
ENSXETP00000044013
,
ENSXETT00000044013
Xenbase
XB-GENE-483750
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