Reactome | jun [nucleoplasm]

jun [nucleoplasm]

Stable Identifier

R-XTR-450250

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

JUN, A0A803K0W9

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Cytokine Signaling in Immune system (Xenopus tropicalis)
  - Signaling by Interleukins (Xenopus tropicalis)
    - Interleukin-17 signaling (Xenopus tropicalis)
      - MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
- Innate Immune System (Xenopus tropicalis)
  - Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
    - FCERI mediated MAPK activation (Xenopus tropicalis)
      - Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
  - Toll-like Receptor Cascades (Xenopus tropicalis)
    - Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
      - Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
      - Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
      - MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
      - MyD88-independent TLR4 cascade (Xenopus tropicalis)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
      - MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)
    - Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
      - MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
        
        MAP kinase activation (Xenopus tropicalis)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Xenopus tropicalis)
        
        Activation of the AP-1 family of transcription factors (Xenopus tropicalis)
        
        Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)
        
        jun [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A803K0W9

Gene Names

jun

Reference Genes

BioGPS Gene:100493911 jun

ENSEMBL:ENSXETG00000046489

KEGG:xtr:100493911 jun

Monarch:100493911 jun

NCBI Gene:100493911 jun

UCSC:A0A803K0W9 jun

Reference Transcript

RefSeq:XM_031900902.1 jun

Other Identifiers

100493911

GO:0000978

GO:0000981

GO:0003677

GO:0003700

GO:0005667

GO:0006355

GO:0042127

GO:0045944

GO:0048545

GO:0051726

Participates

as an input of

Activated JNKs phosphorylate c-JUN (Xenopus tropicalis)

as a component of

FOS:JUN [nucleoplasm] (Xenopus tropicalis)

Other forms of this molecule

phospho-jun [nucleoplasm]

Inferred From

JUN [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSXETT00000106633, ENSXETG00000046489, ENSXETP00000113919

Xenbase

XB-GENE-482228

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