Reactome | krt8 [cytosol]

krt8 [cytosol]

Stable Identifier

R-XTR-446043

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

KRT8, Q6NVR6

Locations in the PathwayBrowser

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Developmental Biology (Xenopus tropicalis)

- Keratinization (Xenopus tropicalis)
  - Formation of the cornified envelope (Xenopus tropicalis)
    - Fillagrin and keratin intermediate filaments polymerize forming a network (Xenopus tropicalis)
      - FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Xenopus tropicalis)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Xenopus tropicalis)
        
        Keratin tonofilament [cytosol] (Xenopus tropicalis)
        
        Keratin filament [cytosol] (Xenopus tropicalis)
        
        Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
      - FLG-Keratin filament network [plasma membrane] (Xenopus tropicalis)
        
        FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Xenopus tropicalis)
        
        Keratin tonofilament:Desmosome [plasma membrane] (Xenopus tropicalis)
        
        Keratin tonofilament [cytosol] (Xenopus tropicalis)
        
        Keratin filament [cytosol] (Xenopus tropicalis)
        
        Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
  - Formation of tonofilament bundles (Xenopus tropicalis)
    - Keratin filament [cytosol] (Xenopus tropicalis)
      - Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
    - Keratin tonofilament [cytosol] (Xenopus tropicalis)
      - Keratin filament [cytosol] (Xenopus tropicalis)
        
        Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
  - Keratin filament formation (Xenopus tropicalis)
    - Keratin filament [cytosol] (Xenopus tropicalis)
      - Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
    - Keratin filament units [cytosol] (Xenopus tropicalis)
      - Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
      - Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
  - Keratin filaments bind cell-cell adhesion complexes (Xenopus tropicalis)
    - Keratin tonofilament [cytosol] (Xenopus tropicalis)
      - Keratin filament [cytosol] (Xenopus tropicalis)
        
        Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
    - Keratin tonofilament:Desmosome [plasma membrane] (Xenopus tropicalis)
      - Keratin tonofilament [cytosol] (Xenopus tropicalis)
        
        Keratin filament [cytosol] (Xenopus tropicalis)
        
        Keratin filament units [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
        
        Keratin unit length filament [cytosol] (Xenopus tropicalis)
        
        Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
  - Keratin tetramers bind to form unit length filaments (Xenopus tropicalis)
    - Keratin tetramer [cytosol] (Xenopus tropicalis)
      - Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
    - Keratin unit length filament [cytosol] (Xenopus tropicalis)
      - Keratin tetramer [cytosol] (Xenopus tropicalis)
        
        Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
  - Keratin type I binds keratin type II (Xenopus tropicalis)
    - Keratin heterodimer [cytosol] (Xenopus tropicalis)
      - Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
    - Keratin type II [cytosol] (Xenopus tropicalis)
      - Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
  - Keratin type I/type II heterodimers form tetramers (Xenopus tropicalis)
    - Keratin heterodimer [cytosol] (Xenopus tropicalis)
      - Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)
    - Keratin tetramer [cytosol] (Xenopus tropicalis)
      - Keratin heterodimer [cytosol] (Xenopus tropicalis)
        
        Keratin type II [cytosol] (Xenopus tropicalis)
        
        Keratin type II, epithelial [cytosol] (Xenopus tropicalis)
        
        krt8 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q6NVR6

Gene Names

krt8

Reference Genes

BioGPS Gene:431676 krt8

ENSEMBL:ENSXETG00000020454

KEGG:xtr:431676 krt8

Monarch:431676 krt8

NCBI Gene:431676 krt8

UCSC:Q6NVR6 krt8

Reference Transcript

RefSeq:NM_001002797.2 krt8

Other Identifiers

431676

GO:0005634

GO:0005654

GO:0005737

GO:0005882

GO:0016363

GO:0045095

Participates

as a member of

Keratin type II, epithelial [cytosol] (Xenopus tropicalis)

Inferred From

KRT8 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001002797.1

ENSEMBL

ENSXETP00000079245, ENSXETG00000020454, ENSXETT00000087842

Xenbase

XB-GENE-876929

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