Reactome | nefl [cytosol]

nefl [cytosol]

Stable Identifier

R-XTR-432284

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

NEFL, F6TRE5

Locations in the PathwayBrowser

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Neuronal System (Xenopus tropicalis)

- Transmission across Chemical Synapses (Xenopus tropicalis)
  - Neurotransmitter receptors and postsynaptic signal transmission (Xenopus tropicalis)
    - Activation of NMDA receptors and postsynaptic events (Xenopus tropicalis)
      - Unblocking of NMDA receptors, glutamate binding and activation (Xenopus tropicalis)
        
        Ca2+ influx into the post-synaptic cell (Xenopus tropicalis)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Xenopus tropicalis)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Xenopus tropicalis)
        
        nefl [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6TRE5

Gene Names

nefl

Reference Genes

BioGPS Gene:100216135 nefl

ENSEMBL:ENSXETG00000010142

KEGG:xtr:100216135 nefl

Monarch:100216135 nefl

NCBI Gene:100216135 nefl

UCSC:F6TRE5 nefl

Reference Transcript

RefSeq:XM_002932582.5 nefl

Other Identifiers

100216135

GO:0005737

GO:0005856

GO:0005882

GO:0007010

GO:0030424

GO:0033693

GO:0042995

GO:0099160

GO:0099184

GO:0099185

Participates

as a component of

GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Xenopus tropicalis)

Inferred From

NEFL [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_002932628.2

ENSEMBL

ENSXETP00000022374, ENSXETG00000010142, ENSXETT00000022374

Xenbase

XB-GENE-492106

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