Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
sin3a [nucleoplasm]
Stable Identifier
R-XTR-351657
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
nucleoplasm
Synonyms
SIN3A, F6TAI6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Xenopus tropicalis)
MITF-M-regulated melanocyte development (Xenopus tropicalis)
MITF-M-dependent gene expression (Xenopus tropicalis)
Regulation of MITF-M-dependent genes involved in apoptosis (Xenopus tropicalis)
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Xenopus tropicalis)
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Xenopus tropicalis)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Xenopus tropicalis)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by MECP2 (Xenopus tropicalis)
Regulation of MECP2 expression and activity (Xenopus tropicalis)
MECP2 binds the SIN3A co-repressor complex (Xenopus tropicalis)
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Xenopus tropicalis)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1 homodimer [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
MECP2:SIN3A:HDAC2 [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC2 homodimer [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1 homodimer [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC2 homodimer [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
Transcriptional regulation by RUNX1 (Xenopus tropicalis)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Xenopus tropicalis)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Xenopus tropicalis)
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Regulation of lipid metabolism by PPARalpha (Xenopus tropicalis)
PPARA binds fibrates (Xenopus tropicalis)
Corepressors of PPARalpha [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
PPARA:RXRA:Corepressors [nucleoplasm] (Xenopus tropicalis)
Corepressors of PPARalpha [nucleoplasm] (Xenopus tropicalis)
sin3a [nucleoplasm] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F6TAI6
Gene Names
sin3a
Reference Genes
BioGPS Gene:100495645 sin3a
ENSEMBL:ENSXETG00000015283
KEGG:xtr:100495645 sin3a
Monarch:100495645 sin3a
NCBI Gene:100495645 sin3a
UCSC:F6TAI6 sin3a
Reference Transcript
RefSeq:XM_012966900.3 sin3a
RefSeq:XM_002937477.5 sin3a
RefSeq:XM_012966901.3 sin3a
Other Identifiers
100495645
GO:0000122
GO:0000785
GO:0003714
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0006355
GO:0010558
GO:0032991
GO:0045892
GO:0048511
GO:0061629
GO:0070822
Participates
as an input of
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Xenopus tropicalis)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Xenopus tropicalis)
as a component of
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Xenopus tropicalis)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC2 homodimer [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1 homodimer [nucleoplasm] (Xenopus tropicalis)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Xenopus tropicalis)
as a member of
SIN3A,(SIN3B) [nucleoplasm] (Xenopus tropicalis)
Corepressors of PPARalpha [nucleoplasm] (Xenopus tropicalis)
Inferred From
SIN3A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_002937523.2
,
XP_012822355.1
,
XP_012822354.1
ENSEMBL
ENSXETG00000015283
,
ENSXETP00000033424
,
ENSXETT00000033424
Xenbase
XB-GENE-480875
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text