Reactome | nckap1 [cytosol]

nckap1 [cytosol]

Stable Identifier

R-XTR-200979

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

NCKAP1, F6RND8

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
    - Regulation of actin dynamics for phagocytic cup formation (Xenopus tropicalis)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Xenopus tropicalis)
        
        Mother filament:branching complex [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Xenopus tropicalis)
        
        p-Y,S,T-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Xenopus tropicalis)
        
        p-Y,S,T-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
      - ABL phosphorylates WAVEs (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
      - Detachment of WASP/WAVE (Xenopus tropicalis)
        
        Mother filament:branching complex [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Xenopus tropicalis)
        
        p-Y,S,T-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Xenopus tropicalis)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Xenopus tropicalis)
        
        p-Y,S,T-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
      - p-ERK phosphorylates WAVEs and ABI (Xenopus tropicalis)
        
        p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Xenopus tropicalis)
        
        p-Y,S,T-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)
        
        p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        p-Y-WRC [cytosol] (Xenopus tropicalis)
        
        nckap1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6RND8

Gene Names

nckap1

Reference Genes

BioGPS Gene:100379683 nckap1

ENSEMBL:ENSXETG00000001337

Monarch:100379683 nckap1

NCBI Gene:100379683 nckap1

UCSC:F6RND8 nckap1

Reference Transcript

RefSeq:XM_004917909.4 nckap1

Other Identifiers

100379683

GO:0000902

GO:0005886

GO:0007010

GO:0016020

GO:0016477

GO:0030031

GO:0030866

GO:0031209

GO:0031258

GO:0042995

GO:0048812

GO:0048870

Participates

as a candidate of

as a component of

Inferred From

NCKAP1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_004917966.1

ENSEMBL

ENSXETG00000001337, ENSXETP00000002843, ENSXETT00000002843

Xenbase

XB-GENE-949166

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