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sqstm1 [cytosol]
Stable Identifier
R-XTR-193937
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
SQSTM1, F6TMS2
Locations in the PathwayBrowser
Expand all
Autophagy (Xenopus tropicalis)
Macroautophagy (Xenopus tropicalis)
Selective autophagy (Xenopus tropicalis)
Mitophagy (Xenopus tropicalis)
PINK1-PRKN Mediated Mitophagy (Xenopus tropicalis)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Xenopus tropicalis)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Xenopus tropicalis)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Xenopus tropicalis)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
p62 binds ubiquitinated mitochondrial substrates (Xenopus tropicalis)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
p62 links damaged mitochondria to LC3 (Xenopus tropicalis)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Xenopus tropicalis)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
KEAP1-NFE2L2 pathway (Xenopus tropicalis)
SQSTM1 oligomerizes (Xenopus tropicalis)
SQSTM1 oligomer [cytosol] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
TRIM21 ubiquitinates SQSTM1 (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
p75 NTR receptor-mediated signalling (Xenopus tropicalis)
p75NTR signals via NF-kB (Xenopus tropicalis)
p75NTR recruits signalling complexes (Xenopus tropicalis)
TRAF6 is auto-ubiquitinated (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
p62 is recruited and forms a complex with TRAF6 (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
sqstm1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:F6TMS2
Gene Names
sqstm1
Reference Genes
BioGPS Gene:493277 sqstm1
ENSEMBL:ENSXETG00000015913
Monarch:493277 sqstm1
NCBI Gene:493277 sqstm1
UCSC:F6TMS2 sqstm1
Reference Transcript
RefSeq:XM_018092044.2 sqstm1
Other Identifiers
493277
GO:0005634
GO:0005737
GO:0005773
GO:0005776
GO:0008270
GO:0043226
GO:0046872
Participates
as an input of
TRIM21 ubiquitinates SQSTM1 (Xenopus tropicalis)
SQSTM1 oligomerizes (Xenopus tropicalis)
p62 is recruited and forms a complex with TRAF6 (Xenopus tropicalis)
p62 binds ubiquitinated mitochondrial substrates (Xenopus tropicalis)
as a component of
SQSTM1 oligomer [cytosol] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Xenopus tropicalis)
Other forms of this molecule
sqstm1 [cytosol]
phospho-sqstm1 [cytosol]
phospho-sqstm1 [cytosol]
Inferred From
SQSTM1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_017947533.1
ENSEMBL
ENSXETT00000034720
,
ENSXETP00000034720
,
ENSXETG00000015913
Xenbase
XB-GENE-5918988
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