Reactome | phospho-spry1 [cytosol]

phospho-spry1 [cytosol]

Stable Identifier

R-XTR-182933

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

p-Y53-SPRY1, A0A6I8SCT0

Locations in the PathwayBrowser

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Signal Transduction (Xenopus tropicalis)

- Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
  - Signaling by EGFR (Xenopus tropicalis)
    - EGFR downregulation (Xenopus tropicalis)
      - CBL ubiquitinates Sprouty (Xenopus tropicalis)
        
        EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Xenopus tropicalis)
        
        Ub-p-Y53/55-SPRY1/2 [cytosol] (Xenopus tropicalis)
        
        p-Y53/55-SPRY1/2 [cytosol] (Xenopus tropicalis)
        
        phospho-spry1 [cytosol] (Xenopus tropicalis)
        
        EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Xenopus tropicalis)
        
        p-Y53/55-SPRY1/2 [cytosol] (Xenopus tropicalis)
        
        phospho-spry1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A6I8SCT0

Gene Names

spry1

Reference Genes

BioGPS Gene:449470 spry1

ENSEMBL:ENSXETG00000041240

Monarch:449470 spry1

NCBI Gene:449470 spry1

UCSC:A0A6I8SCT0 spry1

Reference Transcript

RefSeq:XM_012960230.3 spry1

Other Identifiers

449470

GO:0005737

GO:0005829

GO:0009966

GO:0016020

GO:0040037

GO:0046580

GO:0048513

GO:0048856

GO:0070373

Participates

as a member of

p-Y53/55-SPRY1/2 [cytosol] (Xenopus tropicalis)

Inferred From

p-Y53-SPRY1 [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 53 (in Homo sapiens)

Coordinate

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_012815684.2

ENSEMBL

ENSXETG00000041240, ENSXETP00000092560, ENSXETT00000074579

Xenbase

XB-GENE-480579

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