Reactome | ski [nucleoplasm]

ski [nucleoplasm]

Stable Identifier

R-XTR-173473

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

SKI, A0A8J0R5Q3

Locations in the PathwayBrowser

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Gene expression (Transcription) (Xenopus tropicalis)

- RNA Polymerase II Transcription (Xenopus tropicalis)
  - Generic Transcription Pathway (Xenopus tropicalis)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Xenopus tropicalis)
        
        Degradation of ubiquitinated SKI/SKIL (Xenopus tropicalis)
        
        Ub-SKI/Ub-SKIL [nucleoplasm] (Xenopus tropicalis)
        
        SKI/SKIL [nucleoplasm] (Xenopus tropicalis)
        
        ski [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A0A8J0R5Q3

Gene Names

ski

Reference Genes

BioGPS Gene:100486949 ski

ENSEMBL:ENSXETG00000015978

Monarch:100486949 ski

NCBI Gene:100486949 ski

UCSC:A0A8J0R5Q3 ski

Reference Transcript

RefSeq:XM_004916154.4 ski

Participates

as an input of

SKI complexes with the Smad complex, suppressing BMP2 signalling (Xenopus tropicalis)

as a component of

p-2S-SMAD1/5/8:SMAD4:SKI [nucleoplasm] (Xenopus tropicalis)

as a member of

SKI/SKIL [nucleoplasm] (Xenopus tropicalis)

Inferred From

SKI [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_004916211.1

Xenbase

XB-GENE-494028

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