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ngf [extracellular region]
Stable Identifier
R-XTR-167034
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
extracellular region
Synonyms
NGF, B3DLC5
Locations in the PathwayBrowser
Expand all
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
p75 NTR receptor-mediated signalling (Xenopus tropicalis)
NFG and proNGF binds to p75NTR (Xenopus tropicalis)
NGF homodimer binds to p75NTR (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
p75NTR regulates axonogenesis (Xenopus tropicalis)
Axonal growth stimulation (Xenopus tropicalis)
NGF binding to p75NTR inactivates RHOA (Xenopus tropicalis)
RHOA:GDP:ARHGDIA:NGFR:NGF [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
p75NTR signals via NF-kB (Xenopus tropicalis)
p75NTR recruits signalling complexes (Xenopus tropicalis)
IRAK interacts with TRAF6 (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
MYD88 dissociates (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
TRAF6 is auto-ubiquitinated (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
p62 is recruited and forms a complex with TRAF6 (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Xenopus tropicalis)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
p75NTR interacts with RIP2 (Xenopus tropicalis)
NGF:p75NTR:RIP2 [plasma membrane] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
mature NGF homodimer:p75NTR [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Expression and Processing of Neurotrophins (Xenopus tropicalis)
NGF processing (Xenopus tropicalis)
Pro-beta-NGF and mature beta-NGF are secreted (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
Activation of TRKA receptors (Xenopus tropicalis)
TRKA activation by NGF (Xenopus tropicalis)
Activated TrkA receptor internalizes to endosomes (Xenopus tropicalis)
Activated TrkA receptor complex [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
The bound receptor dimerizes (Xenopus tropicalis)
beta-NGF dimer:TrkA receptor [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
beta-NGF dimer:TrkA receptor dimer [plasma membrane] (Xenopus tropicalis)
beta-NGF dimer:TrkA receptor [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
beta-NGF dimer binds to TrkA receptor (Xenopus tropicalis)
beta-NGF dimer:TrkA receptor [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
PI3K/AKT activation (Xenopus tropicalis)
Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
Signalling to ERKs (Xenopus tropicalis)
Prolonged ERK activation events (Xenopus tropicalis)
ARMS-mediated activation (Xenopus tropicalis)
ARMS is phosphorylated by active TrkA receptor (Xenopus tropicalis)
Active TrkA receptor:ARMS:Crk complex [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor complex [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor complex [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
C3G stimulates nucleotide exchange on Rap1 (Xenopus tropicalis)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor complex [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
Crk's SH3 domain engages C3G (Xenopus tropicalis)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Xenopus tropicalis)
Activated TrkA receptor complex [plasma membrane] (Xenopus tropicalis)
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
ngf [extracellular region] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:B3DLC5
Gene Names
ngf
Reference Genes
BioGPS Gene:100170161 ngf
ENSEMBL:ENSXETG00000016618
KEGG Gene (Xenopus tropicalis):100170161 ngf
Monarch:100170161 ngf
NCBI Gene:100170161 ngf
Reference Transcript
RefSeq:XM_031895716.1 ngf
RefSeq:XM_031895714.1 ngf
RefSeq:XM_031895715.1 ngf
RefSeq:XM_012956913.3 ngf
RefSeq:NM_001129924.1 ngf
Other Identifiers
100170161
GO:0005102
GO:0005576
Participates
as a component of
mature beta-NGF homodimer [extracellular region] (Xenopus tropicalis)
Other forms of this molecule
ngf [extracellular region]
ngf [Golgi lumen]
ngf [cytosol]
ngf [Golgi lumen]
Inferred From
NGF [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_031751575.1
,
XP_012812367.1
,
NP_001123396.1
,
XP_031751574.1
,
XP_031751576.1
Xenbase
XB-GENE-1013200
Ensembl
ENSXETP00000106287
,
ENSXETP00000107800
,
ENSXETT00000120379
,
ENSXETT00000121327
,
ENSXETG00000016618
,
ENSXETP00000113553
,
ENSXETT00000117512
,
ENSXETT00000112956
,
ENSXETP00000118223
,
ENSXETP00000036251
,
ENSXETP00000116221
,
ENSXETT00000118720
,
ENSXETP00000105315
,
ENSXETT00000036251
,
ENSXETT00000112503
,
ENSXETT00000109400
,
ENSXETP00000116736
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