Reactome | socs6 [cytosol]

socs6 [cytosol]

Stable Identifier

R-XTR-1469969

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

SOCS6, A4IH56

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Neddylation (Xenopus tropicalis)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs6 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs6 [cytosol] (Xenopus tropicalis)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Xenopus tropicalis)
        
        CRL E3 ubiquitin ligases [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs6 [cytosol] (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs6 [cytosol] (Xenopus tropicalis)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Xenopus tropicalis)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs6 [cytosol] (Xenopus tropicalis)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Xenopus tropicalis)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Xenopus tropicalis)
        
        CUL5-box protein [cytosol] (Xenopus tropicalis)
        
        socs6 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:A4IH56

Gene Names

socs6

Reference Genes

BioGPS Gene:100124796 socs6

ENSEMBL:ENSXETG00000048969

KEGG:xtr:100124796 socs6

Monarch:100124796 socs6

NCBI Gene:100124796 socs6

UCSC:A4IH56 socs6

Reference Transcript

RefSeq:NM_001102770.1 socs6

Other Identifiers

100124796

GO:0005829

GO:0009968

GO:0016567

GO:0035556

GO:0035591

GO:0040008

GO:0060090

Participates

as an input of

Active FLT3 binds to SOCS6 (Xenopus tropicalis)

as a component of

active FLT3:SOCS6 [plasma membrane] (Xenopus tropicalis)

as a member of

CUL5-box protein [cytosol] (Xenopus tropicalis)

Inferred From

SOCS6 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001096240.1

ENSEMBL

ENSXETP00000119312, ENSXETG00000048969, ENSXETT00000117156

Xenbase

XB-GENE-5747205