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epas1 [cytosol]
Stable Identifier
R-XTR-1234149
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
2xHP-EPAS1, Q6GL61
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to hypoxia (Xenopus tropicalis)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Xenopus tropicalis)
Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
Proteasome proteolyzes ub-HIF-alpha (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Neddylation (Xenopus tropicalis)
26S proteasome degrades HIFalpha (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Xenopus tropicalis)
ub-hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Xenopus tropicalis)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
epas1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:Q6GL61
Gene Names
epas1
Reference Genes
BioGPS Gene:448117 epas1
ENSEMBL:ENSXETG00000026167
KEGG:xtr:448117 epas1
Monarch:448117 epas1
NCBI Gene:448117 epas1
UCSC:Q6GL61 epas1
Reference Transcript
RefSeq:NM_001005647.1 epas1
Participates
as a member of
hydroxyPro-HIF-alpha [cytosol] (Xenopus tropicalis)
Other forms of this molecule
epas1 [cytosol]
epas1 [nucleoplasm]
epas1 [nucleoplasm]
epas1 [cytosol]
Inferred From
2xHP-EPAS1 [cytosol]
(Homo sapiens)
Modified Residues
Name
monohydroxylated proline at 405 (in Homo sapiens)
Coordinate
405
PsiMod Name
monohydroxylated proline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline.
Name
monohydroxylated proline at 531 (in Homo sapiens)
Coordinate
531
PsiMod Name
monohydroxylated proline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline.
Cross References
RefSeq
NP_001005647.1
Xenbase
XB-GENE-981612
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