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Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]
Stable Identifier
R-XTR-1112594
Type
Complex
Species
Xenopus tropicalis
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Xenopus tropicalis)
Cell junction organization (Xenopus tropicalis)
Cell-cell junction organization (Xenopus tropicalis)
Adherens junctions interactions (Xenopus tropicalis)
Activation of STAT3 by cadherin engagement (Xenopus tropicalis)
IL6ST is tyrosine phosphorylated (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6ST binds STAT3 (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylation of STAT3 by IL6 receptor (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:p-Y705-STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
p-Y705-STAT3 dissociates from IL6 receptor (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:p-Y705-STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Immune System (Xenopus tropicalis)
Cytokine Signaling in Immune system (Xenopus tropicalis)
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-6 family signaling (Xenopus tropicalis)
Interleukin-6 signaling (Xenopus tropicalis)
IL6ST is tyrosine phosphorylated (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
PTPN11 binds p-Y759-IL6ST (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
PTPN11 is phosphorylated (Xenopus tropicalis)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Phosphorylated STATs are released (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
SOCS3 binds IL6ST (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Serine phosphorylation of STATs (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Xenopus tropicalis)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane]
(Xenopus tropicalis)
Participates
as an input of
SOCS3 binds IL6ST (Xenopus tropicalis)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Xenopus tropicalis)
PTPN11 binds p-Y759-IL6ST (Xenopus tropicalis)
Tyrosine phosphorylated IL6ST binds STAT3 (Xenopus tropicalis)
as a component of
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT3 [plasma membrane] (Xenopus tropicalis)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:p-Y705-STAT3 [plasma membrane] (Xenopus tropicalis)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Xenopus tropicalis)
as an output of
Phosphorylated STATs are released (Xenopus tropicalis)
p-Y705-STAT3 dissociates from IL6 receptor (Xenopus tropicalis)
IL6ST is tyrosine phosphorylated (Xenopus tropicalis)
Inferred From
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]
(Homo sapiens)
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