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GBP1 [cytosol]
Stable Identifier
R-SSC-9947912
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
S-farn-C589-GBP1, A0A287BSF6
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antimicrobial mechanism of IFN-stimulated genes (Sus scrofa)
GBP-mediated host defense (Sus scrofa)
GBP1 binds GTP (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
S-farn-GBP1:GTP [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 binds actin (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1:G-actin [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 hydrolyzes GDP (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1:GBP2:GBP3:GBP4 forms higher-order structures (Sus scrofa)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GTP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1:GTP binds LPS on the bacterial surface (Sus scrofa)
S-farn-GBP1:GTP [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
S-farn-GBP1:GTP:LPS [peptidoglycan-based cell wall] (Sus scrofa)
S-farn-GBP1:GTP [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP2, GBP3, GBP4 bind to GBP1 oligomer on the bacterial surface (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GTP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GMP dissociates from the GBP1 oligomer (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
Regulation of GBP-mediated host defense (Sus scrofa)
PIM1 phosphorylates GBP1 (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
S-farn-GBP1:GTP [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Non-canonical inflammasome activation (Sus scrofa)
CASP4 inflammasome assembly (Sus scrofa)
CASP4 binds exposed LPS on the bacterial surface (Sus scrofa)
CASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Sus scrofa)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
CASP4 forms dimers on the bacterial surface (Sus scrofa)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Sus scrofa)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
CASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Sus scrofa)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Sus scrofa)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Sus scrofa)
LPS-bound GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
GBP1 oligomer:GMP:LPS [cytosol] (Sus scrofa)
GBP1 oligomer [cytosol] (Sus scrofa)
GBP1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A287BSF6
Gene Names
GBP1
Reference Genes
BioGPS Gene:100151938 GBP1
ENSEMBL:ENSSSCG00000024973.4
Monarch:100151938 GBP1
NCBI Gene:100151938 GBP1
UCSC:A0A287BSF6 GBP1
Reference Transcript
RefSeq:XM_021088504.1 GBP1
RefSeq:XM_021088503.1 GBP1
Other Identifiers
100151938
GO:0001530
GO:0002376
GO:0003779
GO:0003924
GO:0003925
GO:0004382
GO:0005525
GO:0005737
GO:0005794
GO:0005829
GO:0005856
GO:0008092
GO:0008289
GO:0012506
GO:0015629
GO:0016787
GO:0019003
GO:0019899
GO:0019955
GO:0030507
GO:0031410
GO:0032703
GO:0042742
GO:0042802
GO:0042803
GO:0042832
GO:0045087
GO:0050848
GO:0050860
GO:0051604
GO:0051715
GO:0051879
GO:0065003
GO:0070373
GO:0071346
GO:0071347
GO:0071356
GO:0072665
GO:0098542
GO:0098772
GO:0106139
GO:0140639
GO:0160075
GO:1900025
GO:1903076
GO:1903077
Ssc.29054.1.A1_at
Ssc.29054.2.S1_at
Ssc.29054.3.S1_at
Participates
as an input of
PIM1 phosphorylates GBP1 (Sus scrofa)
GBP1 binds actin (Sus scrofa)
GBP1 binds GTP (Sus scrofa)
as a component of
GBP1:G-actin [cytosol] (Sus scrofa)
S-farn-GBP1:GTP [cytosol] (Sus scrofa)
as an output of
GMP dissociates from the GBP1 oligomer (Sus scrofa)
as a repeated unit of
GBP1 oligomer [cytosol] (Sus scrofa)
Other forms of this molecule
GBP1 [cytosol]
GBP1 [cytosol]
phospho-GBP1 [cytosol]
GBP1 [cytosol]
GBP1 [cytosol]
Inferred From
S-farn-C589-GBP1 [cytosol]
(Homo sapiens)
Modified Residues
Name
S-farnesyl-L-cysteine (farnesyl group) at 589 (in Homo sapiens)
Coordinate
589
Modification
farnesyl group
PsiMod Name
S-farnesyl-L-cysteine [MOD:00111]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-farnesyl-L-cysteine.
Cross References
RefSeq
XP_020944163.1
,
XP_020944162.1
ENSEMBL
ENSSSCT00000061945
,
ENSSSCG00000024973
,
ENSSSCP00000059373
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