Reactome | RNF5 [endoplasmic reticulum membrane]

RNF5 [endoplasmic reticulum membrane]

Stable Identifier

R-SSC-975990

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

endoplasmic reticulum membrane

Synonyms

RNF5, A5A8Y3

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Adaptive Immune System (Sus scrofa)
  - Regulation of T cell activation by CD28 family (Sus scrofa)
    - Co-inhibition by PD-1 (Sus scrofa)
      - Regulation of PD-L1(CD274) expression (Sus scrofa)
        
        Regulation of PD-L1(CD274) Post-translational modification (Sus scrofa)
        
        AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) (Sus scrofa)
        
        Active transport of ubiquitinated CD274 from ER to cytosol (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Ubiquitination of CD274 by ERAD complex (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)
        
        Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)
        
        p-S195-CD274 binds ERAD complex (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)
        
        RNF5 [endoplasmic reticulum membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A5A8Y3

Gene Names

RNF5

Reference Genes

BioGPS Gene:100144528 RNF5

ENSEMBL:ENSSSCG00005045052.1

KEGG:ssc:100144528 RNF5

Monarch:100144528 RNF5

NCBI Gene:100144528 RNF5

UCSC:A5A8Y3 RNF5

Reference Transcript

RefSeq:NM_001123224.1 RNF5

Other Identifiers

100144528

GO:0003824

GO:0004842

GO:0005783

GO:0005789

GO:0006511

GO:0008270

GO:0009617

GO:0010507

GO:0012505

GO:0016020

GO:0016567

GO:0016740

GO:0030163

GO:0031648

GO:0031966

GO:0036503

GO:0042802

GO:0044390

GO:0044877

GO:0046872

GO:0061630

GO:0070534

GO:0070936

GO:0140096

GO:2000785

Ssc.1246.1.S1_at

Participates

as a member of

RNF5,RNF185 [endoplasmic reticulum membrane] (Sus scrofa)

Inferred From

RNF5 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001116696.1

ENSEMBL

ENSSSCP00000001543, ENSSSCT00000001585, ENSSSCG00000001436

VGNC

92396