Reactome | UBC [cytosol]

UBC [cytosol]

Stable Identifier

R-SSC-939249

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

Ub-48-UBB(1-76), P0CG68

Locations in the PathwayBrowser

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Signal Transduction (Sus scrofa)

- Death Receptor Signaling (Sus scrofa)
  - TNF signaling (Sus scrofa)
    - Regulation of TNFR1 signaling (Sus scrofa)
      - TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Sus scrofa)
        
        K48polyUb [cytosol] (Sus scrofa)
        
        K48-Ub [cytosol] (Sus scrofa)
        
        UBC [cytosol] (Sus scrofa)
        
        K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Sus scrofa)
        
        K48polyUb [cytosol] (Sus scrofa)
        
        K48-Ub [cytosol] (Sus scrofa)
        
        UBC [cytosol] (Sus scrofa)
- MAPK family signaling cascades (Sus scrofa)
  - MAPK1/MAPK3 signaling (Sus scrofa)
    - RAF/MAP kinase cascade (Sus scrofa)
      - RAS processing (Sus scrofa)
        
        USP17L2 deubiquitinates RCE1 (Sus scrofa)
        
        PolyUb [cytosol] (Sus scrofa)
        
        K48polyUb [cytosol] (Sus scrofa)
        
        K48-Ub [cytosol] (Sus scrofa)
        
        UBC [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:P0CG68

Gene Names

UBC

Reference Genes

BioGPS Gene:396966 UBC

ENSEMBL:ENSSSCG00040057990

KEGG:ssc:396966 UBC

Monarch:396966 UBC

NCBI Gene:396966 UBC

UCSC:P0CG68 UBC

Participates

as a member of

K48-Ub [cytosol] (Sus scrofa)

Other forms of this molecule

UBC [endocytic vesicle membrane]

UBC [mitochondrial outer membrane]

UBC [cytosol]

phospho-UBC [nucleoplasm]

UBC [cytosol]

phospho-UBC [cytosol]

UBC [endosome membrane]

UBC [mitochondrial outer membrane]

UBC [cytosol]

UBC [endoplasmic reticulum membrane]

UBC [nucleoplasm]

UBC [cytosol]

UBC [nucleoplasm]

UBC [cytosol]

UBC [nucleoplasm]

Inferred From

Ub-48-UBB(1-76) [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at 48 (in Homo sapiens)

Coordinate

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.