Reactome | CSTF2T [nucleoplasm]

CSTF2T [nucleoplasm]

Stable Identifier

R-SSC-8938786

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

CSTF2T, F1SD01

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA Polymerase II Transcription Termination (Sus scrofa)
    - Cleavage of Intronless Pre-mRNA at 3'-end (Sus scrofa)
      - CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Sus scrofa)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)

Metabolism of RNA (Sus scrofa)

- Processing of Capped Intron-Containing Pre-mRNA (Sus scrofa)
  - mRNA 3'-end processing (Sus scrofa)
    - TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Sus scrofa)
      - Spliced mRNP [nucleoplasm] (Sus scrofa)
        
        Cleavage and Polyadenylation Complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
    - mRNA Polyadenylation (Sus scrofa)
      - Core CPA complex binds capped pre-mRNA (Sus scrofa)
        
        Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - Formation of the CSTF complex (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - Formation of the core cleavage and polyadenylation complex (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Sus scrofa)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - PP1 dephosphorylates RNA Pol II (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Sus scrofa)
        
        CPA complex [nucleoplasm] (Sus scrofa)
        
        Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        CPA complex [nucleoplasm] (Sus scrofa)
        
        Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - RBBP6 activates CPSF complex (Sus scrofa)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        CPA complex [nucleoplasm] (Sus scrofa)
        
        Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Sus scrofa)
        
        Ub-K63-CPA complex [nucleoplasm] (Sus scrofa)
        
        Ub-K63-Core CPA complex [nucleoplasm] (Sus scrofa)
        
        CSTF hexamer [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
- Processing of Capped Intronless Pre-mRNA (Sus scrofa)
  - Processing of Intronless Pre-mRNAs (Sus scrofa)
    - Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Sus scrofa)
      - CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Sus scrofa)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
    - Cleavage and polyadenylation of Intronless Pre-mRNA (Sus scrofa)
      - CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Sus scrofa)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
    - Cleavage of Intronless Pre-mRNA at 3'-end (Sus scrofa)
      - CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - intronless pre-mRNA cleavage complex [nucleoplasm] (Sus scrofa)
        
        CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
    - Recruitment of CstF to the CPSF Bound Pre-mRNA (Sus scrofa)
      - CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)
      - CstF:CPSF:capped intronless pre-mRNA:CBC complex [nucleoplasm] (Sus scrofa)
        
        CSTF heterotrimer [nucleoplasm] (Sus scrofa)
        
        CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)
        
        CSTF2T [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SD01

Gene Names

CSTF2T

Reference Genes

BioGPS Gene:100157243 CSTF2T

ENSEMBL:ENSSSCG00000010430.3

KEGG:ssc:100157243 CSTF2T

Monarch:100157243 CSTF2T

NCBI Gene:100157243 CSTF2T

UCSC:F1SD01 CSTF2T

Reference Transcript

RefSeq:XM_005671248.3 CSTF2T

Other Identifiers

100157243

GO:0003676

GO:0003723

GO:0003729

GO:0005634

GO:0005654

GO:0005847

GO:0006397

GO:0016071

GO:0031124

Ssc.10632.1.A1_at

Participates

as a member of

CSTF2,CSTF2T [nucleoplasm] (Sus scrofa)

Inferred From

CSTF2T [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_005671305.1

ENSEMBL

ENSSSCP00000011119, ENSSSCT00000011415, ENSSSCG00000010430

VGNC

87051

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