Reactome | CD3G [clathrin-coated endocytic vesicle membrane]

CD3G [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-SSC-8869080

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

CD3G, Q5PXD3

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
    - RAB5 and GAPVD1 bind AP-2 (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CD3G [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q5PXD3

Gene Names

CD3G

Reference Genes

BioGPS Gene:494013 CD3G

ENSEMBL:ENSSSCG00065071966

KEGG:ssc:494013 CD3G

Monarch:494013 CD3G

NCBI Gene:494013 CD3G

UCSC:Q5PXD3 CD3G

Reference Transcript

Participates

as a member of

AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

Other forms of this molecule

CD3G [plasma membrane]

phospho-CD3G [plasma membrane]

Inferred From

CD3G [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

XP_005653762.1, XP_005653763.1, XP_005653764.1, NP_001008686.1

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