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HMGB1 [extracellular region]
Stable Identifier
R-SSC-879382
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
extracellular region
Synonyms
HMGB1, A0A8W4FKZ0
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Innate Immune System (Sus scrofa)
Advanced glycosylation endproduct receptor signaling (Sus scrofa)
Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
TRAF6 mediated NF-kB activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Neutrophil degranulation (Sus scrofa)
Exocytosis of ficolin-rich granule lumen proteins (Sus scrofa)
Ficolin-rich granule lumen proteins [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Exocytosis of secretory granule lumen proteins (Sus scrofa)
Secretory granule lumen proteins [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
NF-kappa-B complex is transported from cytosol to nucleus (Sus scrofa)
AGER ligands:AGER [plasma membrane] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
Vesicle-mediated transport (Sus scrofa)
Binding and Uptake of Ligands by Scavenger Receptors (Sus scrofa)
Scavenging by Class B Receptors (Sus scrofa)
CD5L (AIM) binds damage-associated patterns (DAMPs) (Sus scrofa)
CD5L:DAMP ligand [extracellular region] (Sus scrofa)
DAMP ligand of CD5L [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
DAMP ligand of CD5L [extracellular region] (Sus scrofa)
HMGB1 [extracellular region] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A8W4FKZ0
Gene Names
HMGB1
Reference Genes
BioGPS Gene:445521 HMGB1
ENSEMBL:ENSSSCG00000009327.5
Monarch:445521 HMGB1
NCBI Gene:445521 HMGB1
UCSC:A0A8W4FKZ0 HMGB1
Reference Transcript
RefSeq:XM_021065159.1 HMGB1
RefSeq:XM_005668317.3 HMGB1
RefSeq:XM_021065160.1 HMGB1
RefSeq:XM_005668316.3 HMGB1
RefSeq:XM_005668318.3 HMGB1
Other Identifiers
445521
GO:0000400
GO:0000405
GO:0000785
GO:0002221
GO:0002250
GO:0002376
GO:0003677
GO:0005576
GO:0005634
GO:0005694
GO:0005737
GO:0005768
GO:0005793
GO:0005886
GO:0006281
GO:0006303
GO:0006310
GO:0006325
GO:0006334
GO:0006338
GO:0006914
GO:0006935
GO:0006954
GO:0006974
GO:0016020
GO:0032392
GO:0043226
GO:0044378
GO:0045087
GO:0065003
GO:0097100
GO:0098542
GO:1902533
Ssc.11100.1.S1_at
Ssc.11100.1.S2_at
Ssc.22696.1.S1_at
Participates
as a member of
DAMP ligand of CD5L [extracellular region] (Sus scrofa)
Secretory granule lumen proteins [extracellular region] (Sus scrofa)
Ficolin-rich granule lumen proteins [extracellular region] (Sus scrofa)
AGER ligands [extracellular region] (Sus scrofa)
Other forms of this molecule
HMGB1 [secretory granule lumen]
HMGB1 [ficolin-1-rich granule lumen]
HMGB1 [nucleoplasm]
HMGB1 [extracellular region]
Inferred From
HMGB1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
XP_020920819.1
,
XP_020920818.1
,
XP_005668373.2
,
XP_005668375.2
,
XP_005668374.2
ENSEMBL
ENSSSCG00000009327
,
ENSSSCT00000098183
,
ENSSSCP00000079872
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