Reactome | RPS10 [cytosol]

RPS10 [cytosol]

Stable Identifier

R-SSC-72325

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

RPS10, F1RZ28

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Sus scrofa)

- Nonsense-Mediated Decay (NMD) (Sus scrofa)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Sus scrofa)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Sus scrofa)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
    - SMG6 hydrolyzes mRNA with premature termination codon (Sus scrofa)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Sus scrofa)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Sus scrofa)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Sus scrofa)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Sus scrofa)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Sus scrofa)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Sus scrofa)
        
        80S ribosome [cytosol] (Sus scrofa)
        
        40S ribosomal complex [cytosol] (Sus scrofa)
        
        RPS10 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RZ28

Gene Names

RPS10

Reference Genes

ENSEMBL:ENSSSCG00000060493.1

UCSC:F1RZ28 RPS10

Other Identifiers

100155444

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0022626

GO:0022627

GO:0045202

GO:1990904

Ssc.23186.1.A1_at

Participates

as a component of

40S ribosomal complex [cytosol] (Sus scrofa)

Other forms of this molecule

RPS10 [nucleoplasm]

RPS10 [cytosol]

Inferred From

RPS10 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000001703, ENSSSCP00000001659, ENSSSCG00000060493

PDB

3J7P

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